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DeCS
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Descriptor English:
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Estrogenic Steroids, Alkylated
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Descriptor Spanish:
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esteroides estrogénicos alquilados
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Descriptor Portuguese:
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Esteroides Estrogênicos Alquilados
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Synonyms English:
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Alkyl Estrogenic Steroids
Alkylated Estrogenic Steroids
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Tree Number:
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D06.472.334.851.437.968
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Definition English:
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Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties. |
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Pharmacological Action:
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Estrogens
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History Note English:
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2004
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Allowable Qualifiers English:
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Record Number:
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38106
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Unique Identifier:
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D042782
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Occurrence in VHL:
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Similar:
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DeCS
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